Metamor Panic: Doki Doki Yōma Busters!! is a visual novel-style adventure game with RPG elements. The adventure scenes mostly proceed linearly, with the player occasionally asked to choose an action, such as choosing what subject to ask a character about, or investigating a certain object. Combat sequences will also occasionally occur, which take a standard turn-based JRPG format where the three characters fight against yōkai. The game doesn't simply use the trappings of an RPG for flavor; it includes leveling up, character stats, and item management and, unlike many games in this style, there is the possibility of losing fights leading to a game over.